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Understanding Pharmacogenetics

The study of drug interaction with an individual's genetic makeup can provide a critical piece of information to aid clinicians when selecting a patient's medication and initial dosage.  This helps eliminate adverse drug reactions or lack of therapeutic effect under standard therapy conditions.

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INTERMEDIATE METABOLIZER

ULTRA-RAPID METABOLIZER

SLOW (POOR) METABOLIZER

Normal metabolizers, also referred to as "Rapid metabolizers" metabolize medications normally  and typically are prescribed according to guidelines intended by the drug's manufacturer and attending physician

Drugs can be broken down too quickly or improperly, requiring a higher dosage or change in medication in many cases.

Drugs are not metabolized fast enough resulting in either too little or too much of the drug in the body.

Drugs, supplements and some foods will reduce or increase the effectiveness of the medication.

Adverse Drug Events in Outpatient Setting an 11 year National Analysis

 

 

 

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AMA Warfarin Brochure - Personalized health care report 2008: Warfarin and genetic testing

 

 

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Codeine Toxicity to Breastfed Childand├▒ Safety of codeine during breastfeeding

 

 

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Coumadin Article: Warfarin Genotyping Reduces Hospitalization Rates

 

 

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Bad medicine: The awful drug reactions Americans report - The Washington Post ├▒ New data released by the U.S. Food and Drug Administration on bad reactions to drugs show men and women having vastly different experiences.

 

 

 

PGX and Whitepaper Compilation - A collection of articles about Pharmacogenetics and its use in prescribing and patient care

 

 

 

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